Acta Vet. Brno 2010, 79: 443-448

https://doi.org/10.2754/avb201079030443

Modulation of Tularemia Disease Progress by the Bisquaternary Pyridinium Oxime HI-6

Miroslav Pohanka1,2, Oto Pavliš3,4, Jiří Pikula5, František Treml6, Kamil Kuca2,7

1Centre of Advanced Studies, Faculty of Military Health Sciences, University of Defence, Hradec Králové, Czech Republic
2Department of Toxicology, Faculty of Military Health Sciences, University of Defence, Hradec Králové, Czech Republic
3Centre of Biological Defence, Těchonín, Czech Republic
4Department of Toxicology, Faculty of Military Health Sciences, University of Defence, Hradec Králové, Czech Republic
5Department of Veterinary Ecology and Environmental Protection, Faculty of Veterinary Hygiene and Ecology
6Department of Infectious Diseases and Epizootiology, Faculty of Veterinary Medicine, University of Veterinary and Pharmaceutical Sciences Brno, Czech Republic
7Centre of Advanced Studies, Faculty of Military Health Sciences, University of Defence, Hradec Králové, Czech Republic

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  • Pohanka Miroslav: Alpha7 Nicotinic Acetylcholine Receptor Is a Target in Pharmacology and Toxicology. IJMS 2012, 13, 2219. <https://doi.org/10.3390/ijms13022219>
  • Pohanka Miroslav, Novotny Ladislav, Zdarova-Karasova Jana, Bandouchova Hana, Zemek Filip, Hrabinova Martina, Misik Jan, Kuca Kamil, Bajgar Jiri, Zitka Ondrej, Cernei Natalia, Kizek Rene, Pikula Jiri: Asoxime (HI-6) impact on dogs after one and tenfold therapeutic doses: Assessment of adverse effects, distribution, and oxidative stress. Environmental Toxicology and Pharmacology 2011, 32, 75. <https://doi.org/10.1016/j.etap.2011.03.014>
  • Pohanka Miroslav, Sobotka Jakub, Svobodova Hana, Stetina Rudolf: Investigation of oxidative stress in blood, brain, kidney, and liver after oxime antidote HI-6 application in a mouse experimental model. Drug and Chemical Toxicology 2011, 34, 255. <https://doi.org/10.3109/01480545.2010.542753>
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