Acta Vet. Brno 2011, 80: 385-390

https://doi.org/10.2754/avb201180040385

Evaluation of toxicity after periocular and intravitreal administration of carboplatin in rabbit eyes

Denisa Darsová1, Pavel Pochop1, Luděk Vajner2, Daniela Kodetová3, Jiří Uhlík2, Jiří Kukačka4, Dagmar Dotřelová1

1Department of Ophthalmology for Children and Adults, Charles University 2nd Faculty of Medicine and Motol Hospital, Prague, Czech Republic
2Department of Histology and Embryology, Charles University 2nd Faculty of Medicine, Prague, Czech Republic
3Department of Pathology and Molecular Medicine, Charles University 2nd Faculty of Medicine and Motol Hospital, Prague, Czech Republic
4Department of Clinical Biochemistry and Pathobiochemistry, Charles University 2nd Faculty of Medicine and Motol Hospital, Prague, Czech Republic

References

1. Abramson DH, Frank ChM, Dunkel IJ 1999: A phase I/II study of subconjunctival carboplatin for intraocular retinoblastoma. Ophthalmol 106: 1947-1950 <https://doi.org/10.1016/S0161-6420(99)90406-2>
2. Abramson DH, Schefler AC 2004: Update on retinoblastoma. Retina 24: 828-848 <https://doi.org/10.1097/00006982-200412000-00002>
3. Benz MS, Scott IU, Murray TG, Kramer D, Toledano S 2000: Complications of systemic chemotherapy as treatment of retinoblastoma. Arch Ophthalmol 118: 577-578
4. Brouwers EE, Tibben MM, Joerger M, van Tellingen O, Rosing H, Schellens JH, Beijnen JH 2005: Determination of oxaliplatin in human plasma and plasma ultrafiltrate by graphite-furnace atomic-absorption spectrometry. Anal Bioanal Chem 382: 1484-1490 <https://doi.org/10.1007/s00216-005-3302-5>
5. Davis FA 1929: The anatomy and histology of the eye and orbit of the rabbit. Trans Am Ophthalmol Soc 27: 400-441
6. Fugaro MN, Kiupel M, Montiani-Ferreira F, Hawkins JF, Janovitz EB 2005: Retinoblastoma in the eye of a llama (Llama glama). Vet Ophthalmol 8: 287-290 <https://doi.org/10.1111/j.1463-5224.2005.00407.x>
7. Graham MA, Lockwood GF, Greenslade D, Brienza S, Bayssas M, Gamelin E 2000: Clinical pharmacokinetics of oxaliplatin: a critical review. Clin Can Res 6: 1205-1218
8. Hayden BC, Jockovich ME, Murray TG, Voigt M, Milne P, Kralinger M, Feuer WJ, Hernandez E, Parel JM 2004: Pharmacokinetics of systemic versus focal carboplatin chemotherapy in the rabbit eye: possible implication in the treatment of retinoblastoma. Invest Ophthalmol Vis Sci 45: 3644-3649 <https://doi.org/10.1167/iovs.04-0228>
9. Jensen OA, Kaarsholm S, Prause JU, Heegaard S 2003: Neuroepithelial tumor of the retina in a dog. Vet Ophthalmol 6: 57-60 <https://doi.org/10.1046/j.1463-5224.2003.00268.x>
10. Kane A, Barza M, Baum J 1981: Intravitreal injection of gentamicin in rabbits. Effect of inflammation and pigmentation on half-life and ocular distribution. Invest Ophthalmol Vis Sci 20: 593-597
11. Kaneko A, Suzuki S 2003: Eye-preservation treatment of retinoblastoma with vitreous seeding. Jpn J Clin Oncol 33: 601-607 <https://doi.org/10.1093/jjco/hyg113>
12. Kim JW, Yau JW, Moshfeghi D, Fishman M 2010: Orbital fibrosis and intraocular recurrence of retinoblastoma following periocular carboplatin. J Pediatr Ophthalmol Strabismus 47: 1-4 <https://doi.org/10.3928/01913913-20090918-08>
13. Knottenbelt DC, Hetzel U, Roberts V 2007: Primary intraocular primitive neuroectodermal tumor (retinoblastoma) causing unilateral blindness in a gelding. Vet Ophthalmol 10: 348-356 <https://doi.org/10.1111/j.1463-5224.2007.00567.x>
14. Kukacka J, Tesfaye H, Malis J, Adam V, Fabrik I, Kotaska K, Stary J, Kizek R, Prusa R 2008: Carboplatin monitoring by flameless atomic absorption spectrophotometry and metallothionein levels in pediatric patients with solid tumors. Clin Chem 54, A11
15. Mendelsohn ME, Abramson DH, Madden T, Tong W, Tran HT, Dunkel IJ 1998: Intraocular concentrations of chemotherapeutic agents after systemic or local administration. Arch Ophthalmol 116: 1209-1212 <https://doi.org/10.1001/archopht.116.9.1209>
16. Mulvihill A, Budning A, Jay V, Vandenhoven C, Heon E, Gallie BL, Chan HSL 2003: Ocular motility changes after subtenon carboplatin chemotherapy for retinoblastoma. Arch Ophthalmol 121: 1120-1124 <https://doi.org/10.1001/archopht.121.8.1120>
17. Nork MT, Kim CHBY, Shanmuganayagam D, Van Lysel MS, Ver Hoeve JN, Folts JD 2006: Measurement of regional choroidal blood flow in rabbits and monkeys using fluorescent microspheres. Arch Ophthalmol 124: 860-868 <https://doi.org/10.1001/archopht.124.6.860>
18. Pardue MT, Hejny CH, Gilbert JA, Phillips MJ, Geroski DH, Edelhauser HF 2004: Retinal function after subconjunctival injection of carboplatin in fibrin sealant. Retina 24: 776-782 <https://doi.org/10.1097/00006982-200410000-00015>
19. Pochop P, Darsova D, Kukacka J, Tesfaye H, Vajner L, Uhlik J, Kodetová D, Malis J, Dotrelova D 2010: Intravitreal carboplatin concentration and area under concentration versus time curve after intravitreal and periocular delivery. Europ J Ophthalmol 20:745-751 <https://doi.org/10.1177/112067211002000416>
20. Schmack I, Hubbard GB, Kang SJ, Aaberg TM Jr, Grossniklaus HE 2006: Ischemic necrosis and atrophy of the optic nerve after periocular carboplatin injection for intraocular retinoblastoma. Am J Ophthalmol 142: 310-315 <https://doi.org/10.1016/j.ajo.2006.02.044>
21. Shields CL, Shields JA, Cater J, Othmane I, Singh AD, Micaily B 2001: Plaque radiotherapy for retinoblastoma: long-term tumor control and treatment complications in 208 tumors. Ophthalmol 108: 2116-2121 <https://doi.org/10.1016/S0161-6420(01)00797-7>
22. Shields CL, Honavar SG, Meadows AT, Shields JA, Demirci H, Singh A, Friedman DL, Naduvilath TJ 2002: Chemoreduction plus focal therapy for retinoblastoma: factors predictive of need for treatment with external beam radiotherapy or enucleation. Am J Ophthalmol 133: 657-664 <https://doi.org/10.1016/S0002-9394(02)01348-X>
23. Syed NA, Nork TM, Poulsen GL, Riis RC, George C, Albert DM 1997: Retinoblastoma in a dog. Arch Ophthalmol 115: 758-763 <https://doi.org/10.1001/archopht.1997.01100150760012>
24. Van Quill K, Dioguardi P, Tong C, Gilbert J, Aaberg T Jr , Grossniklaus H, Edelhauser H, O’Brien J 2005: Subconjunctival carboplatin in fibrin sealant in the treatment of transgenic murine retinoblastoma. Ophthalmol 112: 1151-1158 <https://doi.org/10.1016/j.ophtha.2004.11.060>
front cover
  • ISSN 0001-7213 (printed)
  • ISSN 1801-7576 (electronic)

Current issue

Archive