Acta Vet. Brno 2012, 81: 153-158

https://doi.org/10.2754/avb201281020153

A modified high performance liquid chromatographic method for simultaneous quantification of skatole and indole in porcine plasma

Carl Brunius, Galia Zamaratskaia

Department of Food Science, BioCenter, Swedish University of Agricultural Sciences, Uppsala, Sweden

References

1. Blahova J, Dobsikova R, Svobodova Z, Kalab P 2007: Simultaneous determination of plasma cortisol by high performance liquid chromatography and radioimmunoassay methods in fish. Acta Vet Brno 76: 59-64 <https://doi.org/10.2754/avb200776010059>
2. Blanchard J 1981: Evaluation of the relative efficacy of various techniques for deproteinizing plasma samples prior to high-performance liquid-chromatographic analysis. J Chromatogr 226: 455-460 <https://doi.org/10.1016/S0378-4347(00)86080-6>
3. Claus R, Dehnhard M, Herzog A, Bernal-Barragan H, Giménez T 1993: Parallel measurements of indole and skatole (3-methylindole) in feces and blood plasma of pigs by HPLC. Livest Prod Sci 34: 115-126 <https://doi.org/10.1016/0301-6226(93)90040-O>
4. EC (2002). Decision 2002/657/EC. Official Journal of the European Communities. L221: 8-36: Commission of the European Communities
5. FDA (2001). Guidance for industry: Bioanalytical method validation Rockville, MD: US Department of Health and Human Services, Food and Drug Administration, Center for Drug Evaluation and Research
6. Javed I, Iqbal Z, Zia ur R, Khan MZ, Muhammad F, Aslam B, Sandhu MA, Sultan JI 2009: Disposition kinetics and optimal dosage of ciprofloxacin in healthy domestic ruminant species. Acta Vet Brno 78: 155-162 <https://doi.org/10.2754/avb200978010155>
7. Lin RS, Orcutt MW, Patterson JA, Judge MD 1991: Serum skatole detection using gas chromatography and high performance liquid chromatography. Meat Sci 30: 33-40 <https://doi.org/10.1016/0309-1740(91)90032-L>
8. Petrovic V, Novotny J, Hisira V, Link R, Leng L, Kovac G 2009: The impact of suckling and post-weaning period on blood chemistry of piglets. Acta Vet Brno 78: 365-371 <https://doi.org/10.2754/avb200978030365>
9. Shah VP, Midha KK, Dighe S, McGilveray IJ, Skelly JP, Yacobi A, Layloff T, Viswanathan CT, Cook CE, McDowall RD, Pittman KA, Spector S, Albert KS, Bolton S, Cook CE, Dighe S, Dobrinska M, Doub W, Eichelbaum M, Findlay JWA, Gallicano K, Garland W, Hardy DJ, Hulse JD, Karnes HT, McDowall RD, Lange R, Layloff T, Mason WD, McKay G, McGilveray IJ, Midha KK, Ormsby E, Overpeck J, Pittman KA, Plattenberg HD, Shah VP, Shiu G, Sitar D, Skelly JP, Sorgel F, Spector S, Stewart JT, Viswanathan CT, Yacobi A, Yuh L 1992: Analytical methods validation - Bioavailability, bioequivalence and pharmacokinetic studies. Pharmaceut Res 9: 588-592 <https://doi.org/10.1023/A:1015829422034>
10. Shah VP, Midha KK, Findlay JWA, Hill HM, Hulse JD, McGilveray IJ, McKay G, Miller KJ, Patnaik RN, Powell ML, Tonelli A, Viswanathan CT, Yacobi A 2000: Bioanalytical method validation - A revisit with a decade of progress. Pharmaceut Res 17: 1551-1557 <https://doi.org/10.1023/A:1007669411738>
11. Thompson M, Ellison SLR, Wood R 2002: Harmonized guidelines for single-laboratory validation of methods of analysis - (IUPAC technical report). Pure Appl Chem 74: 835-855 <https://doi.org/10.1351/pac200274050835>
12. Tuomola M, Vahva M, Kallio H 1996: High-performance liquid chromatography determination of skatole and indole levels in pig serum, subcutaneous fat, and submaxillary salivary glands. J Agr Food Chem 44: 1265-1270 <https://doi.org/10.1021/jf950796z>
13. Zamaratskaia G, Babol J, Andersson H, Lundström K 2004a: Plasma skatole and androstenone levels in entire male pigs and relationship between boar taint compounds, sex steroids and thyroxine at various ages. Livest Prod Sci 87: 91-98 <https://doi.org/10.1016/j.livprodsci.2003.09.022>
14. Zamaratskaia G, Babol J, Madej A, Squires EJ, Lundström K 2004b: Age-related variation of plasma concentrations of skatole, androstenone, testosterone, oestradiol-17 beta, oestrone sulphate, dehydroepiandrosterone sulphate, triiodothyronine and IGF-1 in six entire male pigs. Reprod Domest Anim 39: 168-172 <https://doi.org/10.1111/j.1439-0531.2004.00496.x>
15. Zamaratskaia G, Squires EJ 2009: Biochemical, nutritional and genetic effects on boar taint in entire male pigs. Animal 3: 1508-1521 <https://doi.org/10.1017/S1751731108003674>
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