Beta-glucan feeding effect on biochemical and immune responses in vaccinated  and non-vaccinated piglets against proliferative enteropathy

Soročinová, Jana; Reichel, Peter; Mudroňová, Dagmar; Novotný, Jaroslav; Link, Róbert; Lešková, Lenka; Smaržik, Michal; Seidel, Herbert; Húska, Miroslav; Macák, Vladimír; Dobolyová, Soňa; Kovačocyová, Katarína

doi:10.2754/avb201382020153

Acta Veterinaria > Archive > 2013, Vol. 82 > Issue 2 > Beta-glucan feeding effect on…

Acta Vet. Brno 2013, 82: 153-159

https://doi.org/10.2754/avb201382020153

Beta-glucan feeding effect on biochemical and immune responses in vaccinated and non-vaccinated piglets against proliferative enteropathy

Jana Soročinová¹, Peter Reichel¹, Dagmar Mudroňová², Jaroslav Novotný¹, Róbert Link¹, Lenka Lešková³, Michal Smaržik³, Herbert Seidel¹, Miroslav Húska¹, Vladimír Macák¹, Soňa Dobolyová¹, Katarína Kovačocyová¹

¹University of Veterinary Medicine and Pharmacy, Clinical Department for Swine, Košice, Slovakia
²University of Veterinary Medicine and Pharmacy, Department of Microbiology and Immunology, Košice, Slovakia
³University of Veterinary Medicine and Pharmacy, Clinical Department for Ruminants, Košice, Slovakia

The aim of this study was to compare the results of active non-specific immuno-modulation in form of feeding food additive based on beta-glucan to pregnant sows and consecutive specific immuno-modulation by vaccination of their sucklings. Experimental sows were fed feedstuff with preparation on basis of beta-glucan at a 5% concentration from day 14 before parturition until the weaning of piglets; control sows were fed standard feedstuff only. Sucklings were vaccinated with a single dose of 2 ml of oral vaccine Enterisol^® Ileitis one week before weaning. Collection of biological material was done 3 × in sows and 5 × in sucklings. Post-vaccination examination of blood serum for antibodies against L. intracellularis in sucklings in experimental and control groups was negative, probably due to insufficiently long period of rejection of antibiotics-medicated feedstuff and by chlorinated water. With the exception of immunological profile, no essential changes were recorded in the dynamics of other indices of examined profiles in groups of sows in relation to immune-modulation. In groups of sucklings from sows fed beta-glucan supplemented feedstuff significant changes were determined for various indices compared with sucklings from sows fed standard foodstuff. This is the first similar study in pig herds in Slovakia.