Acta Vet. Brno 2014, 83: 133-137

Relationship between serum iron and insulin-like growth factor-I concentrations in 10-day-old calves

Radiša Prodanović1, Danijela Kirovski2, Ivan Vujanac1, Petar Dodovski3, Ljubomir Jovanović2, Horea Šamanc1

1University of Belgrade, Faculty of Veterinary Medicine, Department of Farm Animal Diseases, Belgrade, Serbia
2University of Belgrade, Faculty of Veterinary Medicine, Department of Physiology and Biochemistry, Belgrade, Serbia
3University St Kliment Ohridski-Bitola, Faculty of Veterinary Medicine, Department of Physiology, Bitola, Former Yugoslav Republic of Macedonia


1. Blum JW, Baumrucker CR 2002: Colostral and milk insulin-like growth factors and related substances: Mammary gland and neonatal (intestinal and systemic) targets. Domest Anim Endocrinol 23: 101-110 <>
2. Blum JW, Hammon H 1999: Endocrine and metabolic aspects in milk-fed calves. Domest Anim Endocrinol 17: 219-230 <>
3. Bostedt H, Jekel E, Schramel P 1990: The development of iron and copper concentrations in blood plasma of calves in the first days and weeks of life, equally a contribution to the larvaceous neonatal iron deficiency anemia (in German). Deut Tierärztl Woch 97: 400-403
4. Ceppi A, Blum JW 1994: Effects of growth hormone on growth performance, haematology, metabolites and hormones in iron-deficient veal calves. J Vet Med A 41: 443-458 <>
5. Choi JW, Kim SK 2004: Association of serum insulin-like growth factor-I and erythropoiesis in relation to body iron status. Ann Clin Lab Sci 34: 324-328
6. Cordano P, Hammon HM, Morel C, Zurbriggen A, Blum JW 2000: mRNA of insulin-like growth factor (IGF) quantification and presence of IGF binding proteins, and receptors for growth hormone, IGF-I and insulin, determined by reverse transcribed polymerase chain reaction, in the liver of growing and mature male cattle. Domest Anim Endocrinol 19: 191-208 <>
7. Eisa AMA, Elgebaly LS 2010: Effect of ferrous sulphate on haematological, biochemical and immunological parameters in neonatal calves. Vet Ital 46: 329-335
8. Guilloteau P, Biernat M, Woliński J, Zabielski R 2002: Gut regulatory peptides and hormones of the small gut. In: Zabielski R, Gregory PC, Weström B (Eds). Biology of the Intestine in Growing Animals. Elsevier, Amsterdam, pp. 325-362
9. Hammon H, Blum JW 1998: Metabolic and endocrine traits of neonatal calves are influenced by feeding colostrum for different duration or only milk replacer. J Nutr 128: 624-632 <>
10. Harvey JW 2008: Iron metabolism and its disorders. In: Kaneko JJ, Harvey JW, Bruss ML (Eds): Clinical Biochemistry of Domestic Animals, 6th edn. Academic Press, San Diego, pp. 259-285
11. Kirovski D, Lazarević M, Baričević-Jones I, Nedić O, Masnikosa R, Nikolić JA 2008: Effects of peroral insulin and glucose on circulating insulin-like growth factor-I, its binding proteins and thyroid hormones in neonatal calves. Can J Vet Res 72: 253-258
12. Lindt F, Blum JW 1994: Occurrence of iron deficiency in growing cattle. J Vet Med A 41: 237-246 <>
13. Mohri M, Poorsina S, Sedaghat R 2010: Effects of parenteral supply of iron on RBC parameters, performance, and health in neonatal dairy calves. Biol Trace Elem Res 136: 33-39 <>
14. Moosavian HR, Mohri M, Seifi HA 2010: Effects of parenteral over-supplementation of vitamin A and iron on hematology, iron biochemistry, weight gain, and health of neonatal dairy calves. Food Chem Toxicol 48: 1316-1320 <>
15. Morel I 1996: Iron supply in veal calves (in German). Agrarforschung 3: 53-56
16. Podhorský A, Pehová A, Dvořák R, Pavlata L 2007: Metabolic disorders in dairy calves in postpartum period. Acta Vet Brno 76: 45-53 <>
17. Radostits OM, Gay CC, Blood DC, Hinchcliff KW 2000: Veterinary Medicine, 9th edn. Saunders, Philadelphia, PA, USA, 1 875 p.
18. Tran PV, Fretham SJ, Wobken J, Miller BS 2012: Georgieff MK. Gestational-neonatal iron deficiency suppresses and iron treatment reactivates IGF signaling in developing rat hippocampus. Am J Phys Endo Met 302: 316-324
front cover
  • ISSN 0001-7213 (printed)
  • ISSN 1801-7576 (electronic)

Current issue

Indexed in DOAJ