Acta Vet. Brno 2015, 84: 25-28

Serum concentration of haptoglobin in European mouflon (Ovis musimon L.) from a game reserve

Peter Smitka1, Csilla Tóthová1, Ján Čurlík2, Peter Lazar2, Jozef Bíreš3, Terézia Pošiváková4

1Clinic of Ruminants, University of Veterinary Medicine and Pharmacy in Košice, Košice, Slovak Republic
2Department for Breeding and Disease of Game and Fish, University of Veterinary Medicine and Pharmacy in Košice, Košice, Slovak Republic
3State Veterinary and Food Administration, Bratislava, Slovak Republic
4Presov University, Faculty of Humanities and Natural Sciences, Prešov, Slovak Republic

Received December 9, 2013
Accepted July 23, 2014

Acute phase proteins are used as markers of inflammation and sub-clinical disease, and are considered potential biomarkers for animal health and welfare. The objective of this study was to analyse haptoglobin as the main positive acute phase protein in the mouflon. A total of 30 clinically healthy mouflon of different age and sex, reared in a game reserve, were used for this study. Haptoglobin was determined in blood serum by colorimetric assay with a commercially accessible kit. The mean value of haptoglobin in the herd was 0.215 ± 0.068 mg/ml. There was no significant difference between animals divided by sex: male 0.228 ± 0.073 mg/ml, female 0.202 ± 0.062 mg/ml. The mean value in young animals was higher than the mean value in the adults 0.260 ± 0.081 mg/ml and 0.201 ± 0.059 mg/ml, respectively (P < 0.05). This work was designed to identify the baseline concentration of haptoglobin in a clinically healthy population, thus allowing the comparison of welfare and general health status of the herds or different structured groups within the game reserve. This is the first similar study of haptoglobin as a biomarker in the mouflon.


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