Acta Vet. Brno 2016, 85: 267-276
https://doi.org/10.2754/avb201685030267
Effect of mannan oligosaccharide supplementation on blood and intestinal immune cells, bacteria numbers and performance in weaned pigs
References
1. F, Lacković G, Stokes CR, Valpotić I 2002: Recruitment of intestinal CD45RA+ and CD45RC+ cells induced by a candidate oral vaccine against porcine post-weaning colibacillosis. Vet Immunol Immunopathol 86: 137-146
<https://doi.org/10.1016/S0165-2427(02)00033-8>
2. M, Martin-Orue SM, Taylor-Pickard JA, Perez JF, Gasa J 2008: Use of mannan-oligosaccharides and zinc chelate as growth promoters and diarrhea preventative in weaning pigs: Effects on microbiota and gut function. J Anim Sci 86: 94-101
<https://doi.org/10.2527/jas.2005-686>
3. TM, Johnson RW, Kelley KW, Dawson KA, Moran CA and Pettigrew JE 2012: Effects of mannan oligosaccharide on cytokine secretion by porcine alveolar macrophages and serum cytokine concentrations in nursery pigs. J Anim Sci 90: 657-668
<https://doi.org/10.2527/jas.2011-4310>
4. TM, Johnson RW, Kelley KW, Van Alstine WG, Dawson KA, Moran CA, Pettigrew JE 2011a: Mannan oligosaccharide improves immune responses and growth efficiency of nursery pigs experimentally infected with porcine reproductive and respiratory syndrome virus. J Anim Sci 89: 2592-2602
<https://doi.org/10.2527/jas.2010-3208>
5. TM, Johnson RW, Kelley KW, Van Alstine WG, Dawson KA, Moran CA, Pettigrew JE 2011b: Mannan oligosaccharide modulates gene expression profile in experimentally infected with porcine reproductive and respiratory syndrome virus. J Anim Sci 89: 3016-3029
<https://doi.org/10.2527/jas.2010-3366>
6. ME, Brown DC, Maxwell CV, Johnson ZB, Kegley EB, Dvorak RA 2004a: Effect of phosphorylated mannans and pharmacological additions of zinc oxide on growth and immunocompetence of weanling pigs. J Anim Sci 82: 581-587
<https://doi.org/10.2527/2004.822581x>
7. ME, Maxwell CV, Erf GF, Brown DC, Wistuba TJ 2004b: Dietary supplementation with phosphorylated mannans improves growth response and modulates immune function of weanling pigs. J Anim Sci 82: 1882-1891
<https://doi.org/10.2527/2004.8261882x>
8. N, Ashkenazi S, Mirelman D, Ofek I, Sharon N 1987: Aromatic alpha-glycosides of mannose are powerful inhibitors of the adherence of type 1 fimbriated Escherichia coli to yeast and intestinal epithelial cells. Infect Immunol 55: 472-476
9. M, Rothkǒtter HJ, Bailey M, Stokes CR, Oswald IP 2009: Natural alternatives to in-feed antibiotics in pig production: can immunomodulators play a role? Animal 3: 1644-1661
<https://doi.org/10.1017/S1751731109004236>
10. V, Nochta I 2012: Mannan oligosaccharides in nursery pig nutrition and their potential mode of action. Animals 2: 261-274
<https://doi.org/10.3390/ani2020261>
11. JD, Hyun Y and Sohn K 2000: Effects of mannanoligosaccharide and protein levels on growth performance and immune status in pigs weaned at 21 days of age. J Anim Sci Technol (Korean) 42: 489-498
12. G, Kocher A 2007: Role of yeast cell wall polysaccharides in pig nutrition and health protection. Livestock Sci 109: 161-165
<https://doi.org/10.1016/j.livsci.2007.01.134>
13. A, Lacković G, Božić F, Špoljarić D, Popović M, Valpotić H, Vijtiuk N, Pavičić Ž, Valpotić I 2009: Histomorphometric characteristics of immune cells in small intestine of pigs perorally immunized with vaccine candidate F18ac+ nonenterotoxigenic E. coli strain. Eur J Histochem 53: 189-198
<https://doi.org/10.4081/ejh.2009.e23>
14. G, Vijtiuk N, Ćurić S, Dean-Nystrom EA, Casey TA, Valpotić I 1997: Detection of wCD1, SWC1a, SWC2 and CD45 molecules by immunofluorescence or immunoperoxidase techniques in porcine gut-associated lymphoid tissues following experimentally induced colibacillosis. Period Biol 99: 343-350
15. P, Piao XS, Kim SW, Wang L, Shen YB, Lee HS, Li SY 2008: Effects of chito-oligosaccharide supplementation on the growth performance, nutrient digestability, intestinal morphology, and fecal shedding of Escherichia coli and Lactobacillus in weaning pigs. J Anim Sci 86: 2609-2618
<https://doi.org/10.2527/jas.2007-0668>
16. Lizardo R, Nofrarias M, Guinvarch J, Justin AL, Auclair E, Brufau J 2008: Influence se l’incorporation de levures Saccharmyces cerevisiae ou des leurs parois dans l’aliment sur la digestion et les performances zootechniques des porcelets en post-sevrage. In 40emes Journees de la Recherche Porcine, Paris, France, pp. 183-190
17. RR, Jin LZ, Kim JW, Fang L, Frohlich AA, Baidoo SK 1999: Passive protective effect of egg-yolk antibodies against enterotoxigenic Escherichia coli K88+ infection in neonatal and early-weaned piglets. FEMS Immunol Med Microbiol 23: 283-288
<https://doi.org/10.1111/j.1574-695X.1999.tb01249.x>
18. JC, Rodriguez-Zas SL, Pettigrew JE 2004: Efficacy of a mannan oligosaccharide (Bio-Mos®) for improving nursery pig performance. J Swine Health Prod 12: 296-307
19. NATIONAL RESEARCH COUNCIL 2001: Nutrient Requirements of Pigs. 7th rev. ed. Natl. Acad. Press, Washington, DC, USA.
20. T, Bunchaska C 2011: Effects of sodium gluconate, mannan oligosaccharide and potassium diformate on growth performance and small intestinal morphology of nursery pigs. Asian-Aust. J Anim Sci 24: 844-850
21. H, Schmitz S, Hiss S 2007: Effects of dietary application of a yeast cell wall extract on innate and acquired immunity, on oxidative status and growth performance in weanling piglets and on the ileal epithelium in fattened pigs. J Anim Physiol Anim Nutr 91: 369-380
<https://doi.org/10.1111/j.1439-0396.2006.00663.x>
22. M, Đidara M, Šperanda T, Domaćinović M, Valpotić H, Kovačević J, Antunović Z, Novoselec J 2008: Hydrolyzed brewery yeast product like immunomodulator in weaned piglets. Archiva Zootechnica 11: 52-60
23. H, Mršić G, Gršković B, Špoljarić D, Kezić D, Srečec S, Mataušić-Pišl M, Lacković G, Capak D, Mihelić D, Vlahović, K, Valpotić I, Pirkić A, Anđelinović D, Popović M 2013: Effect of polyoxyethylene and polyoxypropylene nonionic block copolymers on performance and recruitment of immune cell subsets in weaned pigs. Acta Vet Scand 55: 54-62
<https://doi.org/10.1186/1751-0147-55-54>
24. H, Šperanda M, Kovšca-Janjatović A, Đidara M, Lacković G, Božić F, Habrun B, Srečec S, Mataušić-Pišl M, Valpotić I 2014: Levamisole stimulates proliferation of circulating and intestinal immune cell subsets, gut health and performance in weaned pigs. Can J Anim Sci 94: 43-53
<https://doi.org/10.4141/cjas2013-097>
25. H, Terzic S, Vince S, Samardzija M, Turk R, Lackovic G, Habrun B, Djuricic D, Sadikovic M, Valpotic I 2016: In-feed supplementation of a clinoptilolite favourably modulates intestinal and systemic immunity and some production parameters in weaned pigs. Vet Med 61: 317-327
<https://doi.org/10.17221/175/2015-VETMED>
26. I, Vijtiuk N, Trutin-Ostović K, Casey TA, Dean-Nystrom EA, Lacković G 1994: Identification and distribution of CD+ T cell subsets in porcine gut following experimental infection with F4ac+ enterotoxigenic Escherichia coli (ETEC) or non-ETEC strains. Reg Immunol 6: 387-390
27. CMC, Jansman AJM, Smidt H, Yoon I 2007: Effect of yeast culture on performance, gut integrity, and blood cell composition of weanling pigs. J Anim Sci 85: 3099-3109
<https://doi.org/10.2527/jas.2007-0110>
28. BA, Zerby HN, Boler DD, Gebreyes WA, Moeller SJ 2013: Effect of mannan oligosaccharides (Bio-Mos) and outdoor access housing on pig growth, feed efficiency and carcass composition. J Anim Sci 91: 4936-4944
<https://doi.org/10.2527/jas.2013-6582>
29. LA, Newman MC, Cromwell GI, Lindemann MD 2002: Brewers dried yeast as a source of mannan-oligosaccharides for weanling pigs. J Anim Sci 80: 2619-2628
<https://doi.org/10.2527/2002.80102619x>
30. Winn W, Allen S, Janda W, Koneman E, Procop G, Schreckenberger P, Woods G 2006: Koneman’s color atlas and textbook of diagnostic microbiology. 6th edn, (Winn W, Ed.) Lippincott, Williams and Wilkins, London.
31. YL, Tang ZR, Sun ZH, Liu ZQ, Li TJ, Huang RL, Ruan Z, Deng ZY, Gao B, Chen LX, Wu CY, Kim SW 2008: Effect of galacto-mannan-oligosaccharides or chitosan supplementation on cytoimmunity and humoral immunity in early-weaned piglets. Asian-Austral J Anim Sci 21: 723-731
<https://doi.org/10.5713/ajas.2008.70408>
32. PY, Jung JH, Kim IH 2012: Effect of mannan oligosaccharides and fructan on growth performance, nutrient digestibility, blood profile, and diarrhea score in weaned pigs. J Anim Sci 90: 833-839
<https://doi.org/10.2527/jas.2011-3921>

