Acta Vet. Brno 2017, 86: 189-193

Prevalence and epidemiological and histopathological features of canine cutaneous mast cell tumours in Uberlândia, Brazil

Marcelo Carrijo Costa1, Ana Letícia Daher Aprígio Silva2, Thais Almeida Moreira2, Lígia Fernandes Gundim2, Alessandra Aparecida Medeiros-Ronchi2

1Federal University of Uberlândia, Animal Surgery, Uberlândia, Brazil
2Federal University of Uberlândia, Animal Pathology Laboratory, Uberlândia, Brazil

Received March 17, 2016
Accepted May 31, 2017

This study aimed to perform a retrospective survey of canine cutaneous mast cell tumours at the Veterinary Hospital of the Federal University of Uberl‰ndia, as well as to gather epidemiological data, such as breed, age, sex, and location. We also sought to histopathologically classify and characterize the mast cell tumours. Mast cell tumour was the most common neoplasm, accounting for 16.78% of skin neoplasms. In terms of the epidemiological data, the mast cell tumours did not show sexual predilection. Animals aged 9 to 12 years were the most affected (44.14%). The genitalia were the most frequent location (28.15%), and mongrel dogs showed the highest prevalence (30.43%), followed by boxers (22.61%). A total of 92 slides were classified; grade II was most frequently seen (61.96%). Statistically, injuries such as necrosis, oedema, and haemorrhage were not related with histological classification (P > 0.05). Finally, the mitotic index was related to tumour grade (P < 0.05), and can act as an instrument for histological classification of these tumours. Mast cell tumour is the most common neoplasm in dogs, with no sex predilection. Contrary to what was expected, oedema, necrosis and haemorrhage do not increase according to graduation and can be seen in all classifications. Mitotic index is the best indicator to classify these neoplasms.


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