Acta Vet. Brno 2017, 86: 339-344

Correlations between acute phase proteins and the body condition score

Mária Vargová1, Rudolf Hromada1, Katarína Veszelits Laktičová1, Terézia Pošiváková1, Juraj Benculák1, Gabriel Kováč2

1University of Veterinary Medicine and Pharmacy, Department of the Environment, Veterinary Legislation and Economy, Košice, Slovak Republic
2University of Veterinary Medicine and Pharmacy, Clinic of Ruminants, Košice, Slovak Republic

Received November 11, 2016
Accepted October 17, 2017

The objective of this study was to evaluate the dynamics of the body condition score, acute phase proteins (serum amyloid A and haptoglobin) and their relationships in dairy cows of the Slovak Pied Cattle from 3 weeks before parturition to 9 weeks after parturition. Significant differences were found in the means of serum amyloid A (P < 0.01). Haptoglobin concentrations increased from 172.0 ± 0.05 µg/ml to 173.0 ± 0.13 µg/ ml at week 3 and week 1 before the parturition, respectively. The highest value of haptoglobin was recorded in cows 3 week post partum. Cows during the early postparturient period had significantly higher serum amyloid A concentrations compared to cows in the prepartal period (P < 0.01). Significantly higher body condition score values were observed in dry cows (from 4.42 ± 0.20 to 4.25 ± 0.15 points) than in cows after parturition (from 3.90 ± 0.12 to 3.25 ± 0.08 points) (P < 0.001). In the assessment of correlations between the selected acute phase proteins significant positive correlation was found (r = 0.213, P < 0.05). Moreover, negative correlations were found between the body condition score and acute phase proteins. Our results show a strong relationship between the decrease of the body condition score and the increase of acute phase proteins in dairy cows around parturition which indicates the process of a certain form of non-specific inflammation at loss of body fat.


This work was supported by the VEGA Scientific Grant No.1/0203/15 from the Ministry of Education, Science, Research and Sport of the Slovak Republic.


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