Acta Vet. Brno 2017, 86: 365-371

https://doi.org/10.2754/avb201786040365

The effects of iron deficiency on the level of oxidative stress and antioxidant defenses in suckling piglets

Jonáš Vaňhara1, Zdeněk Fajt1, Jana Blahová2, Veronika Tykačová3, Karolína Píšťková3, Martin Hostovský2, Zdenka Kazatelová1, Jan Vašek1, Martin Svoboda1

1University of Veterinary and Pharmaceutical Sciences Brno, Faculty of Veterinary Medicine, Ruminant and Swine Clinic, Brno, Czech Republic
2University of Veterinary and Pharmaceutical Sciences Brno, Faculty of Veterinary Hygiene and Ecology, Department of Animal Welfare, Protection and Behaviour, Brno, Czech Republic
3University of Veterinary and Pharmaceutical Sciences Brno, Faculty of Veterinary Medicine, Large Animal Clinical Laboratory, Brno, Czech Republic

Received October 13, 2017
Accepted December 19, 2017

References

1. Acharya J, Punchard NA, Taylor JA, Thompson RP, Pearson TC 1991: Red cell lipid peroxidation and antioxidant enzymes in iron deficiency. Eur J Haematol 47: 287-291 <https://doi.org/10.1111/j.1600-0609.1991.tb01573.x>
2. Aslan M, Horoz M, Kocyigit A, Ozgonül S, Celik H, Celik M, Erel O 2006: Lymphocyte DNA damage and oxidative stress patients with iron deficiency anemia. Mutat Res 601: 144-149 <https://doi.org/10.1016/j.mrfmmm.2006.06.013>
3. Beyer WF, Fridovich I 1987: Assaying for superoxide dismutase activity: some large consequences of minor changes in conditions. Anal Biochem 161: 559-566 <https://doi.org/10.1016/0003-2697(87)90489-1>
4. Bhattarai S, Nielsen JP 2015: Early indicators of iron deficiency in large piglets at weaning. J Swine Health Prod J 23: 10-17
5. Castegna A, Drake J, Pocernich C, Butterfield DA 2003: Protein carbonyl levels-an assesment of protein oxidation. In: Methods in Biological Oxidative Stress (Methods in Pharmacology and Toxicology), Human Press, pp 161-168
6. Ceron JJ, Martinez-Subiela S 2004: An automated spectrophotometric method for measuring canine ceruloplasmin in serum. Vet Res 35: 671-679 <https://doi.org/10.1051/vetres:2004046>
7. Dalle-Donne I, Rossi R, Giustarini D, Milzani A, Colombo R 2003: Protein carbonyl groups as biomarkers of oxidative stress. Clin Chim Acta 329: 23-38 <https://doi.org/10.1016/S0009-8981(03)00003-2>
8. De Silva DM, Aust SD 1992: Ferritin and ceruloplasmin in oxidative damage: review and recent findings. Can J Physiol Pharmacol 71: 715-720 <https://doi.org/10.1139/y93-107>
9. Fajt Z, Baňoch T, Vašek J, Vaňhara J, Blahová J, Kazatelová Z, Fiorino E, Svoboda M 2016: Influence of iron deficiency on thyroidal hormone production in piglets before weaning. Act Vet Brno 85: 17-22 <https://doi.org/10.2754/avb201685010017>
10. Flohe L, Gunzler WA 1984: Assays of glutathione peroxidase. Met Enz 105: 114-121
11. Han J, Shuvaev VV, Muzykantov VR 2011: Catalase and SOD conjugated with PECAM antibody distinctly alleviate abnormal endothelial permeability caused by exogenous ROS and vascular endothelial growth factor. J Pharmacol Exp Ther 338: 82-91 <https://doi.org/10.1124/jpet.111.180620>
12. Isler M, Delibas N, Guclu M, Gultekin F, Sutcu R, Bahceci M, Kosar A 2002: Superoxide dismutase and glutathione peroxidase in erythrocytes of patients with iron deficiency anemia: Effects of different treatment modalities. Croat Med J 43: 16-19
13. Kumerova A, Lece A, Skesters A, Silova A, Petuhovs V 1998: Anaemia and antioxidant defence of the red blood cells. Mater Med Pol 30: 12-15
14. Levine R, Garland D, Oliver CN 1990: Determination of carbonyl content in oxidatively modified proteins. Met in Enzym 186: 464-478 <https://doi.org/10.1016/0076-6879(90)86141-H>
15. Lushchak VI, Bagnyukova TV, Lushchak OV, Storey JM, Storey KB 2005: Hypoxia and recovery perturb free radical processes and antioxidant potential in common carp (Cyprinus carpio) tissues. Int J Biochem Cell Biol 37: 1319-1330 <https://doi.org/10.1016/j.biocel.2005.01.006>
16. Nagababu E, Gulyani S, Early ChJ, Cutler AG, Mattson MP, Rifkind JM 2008: Iron-deficiency anemia enhances red blood cell oxidative stress. Free Radic Res 42: 824-829 <https://doi.org/10.1080/10715760802459879>
17. Ohkawa H, Ohishi N, Yagi K 1979: Assay for lipid peroxides in animal-tissues by thiobarbituric acid reaction. Anal Biochem 95: 351-358 <https://doi.org/10.1016/0003-2697(79)90738-3>
18. Pi J, Zhang Q, Fu J, Woods CG, Hou Y, Corkey BE, et al. 2010 ROS signaling, oxidative stress and Nrf2 in pancreatic beta-cell function. Toxicol Appl Pharmacol 244: 77-83 <https://doi.org/10.1016/j.taap.2009.05.025>
19. Ranganathan PN, Lu Y, Jiang L, Kim Ch, Collins JF 2011: Serum ceruloplasmin protein expression and activity increases in iron-deficient rats and is further enhanced by higher dietary copper intake. Blood 118: 3146-3153 <https://doi.org/10.1182/blood-2011-05-352112>
20. Re R, Pellegrini N, Proteggente A, Pannala A, Yang M, Rice-Evans C 1999: Antioxidant activity applying an improved ABTS radical cation decolorization assay. Free Radic Biol Med 26: 1231-1237 <https://doi.org/10.1016/S0891-5849(98)00315-3>
21. Rockey DC, Cello JP 1993: Evaluation of the gastrointestinal tract in patients with iron deficiency anemia. N Engl J Med 329: 1691-1695 <https://doi.org/10.1056/NEJM199312023292303>
22. Royston P 1995: A remark on Algorithm AS 181: The W-test for normality. Appl Stat 44: 547-551 <https://doi.org/10.2307/2986146>
23. Svoboda M, Drábek J, Krejčí J, Reháková Z, Faldyna M 2004: Impairment of the peripheral lymphoid compartment in iron-deficient piglets. J Vet Med 51: 231-237 <https://doi.org/10.1111/j.1439-0450.2004.00761.x>
24. Tsaknis J, Stavros L, Michael H, Gillian S, Vassiliki T 1998: Rapid high-performance liquid chromatographic method of determining malondialdehyde for evaluation of rancidity in edible oils. Analyst 123: 325-327 <https://doi.org/10.1039/a706812c>
25. Venn JAJ, McCance RA, Widdowson EM 1947: Iron metabolism in piglet anaemia. J Comp Pathol Ther 57: 314-325 <https://doi.org/10.1016/S0368-1742(47)80037-2>
26. Yin J, Wu MM, Xiao H, Ren WK, Duan JL, Yang G, Li TJ, Yin YL 2014: Development of an antioxidant system after early weaning in piglets. J Animal Sci 92: 612-619 <https://doi.org/10.2527/jas.2013-6986>
27. Yin J, Ren WK, Wu XS, Yang G, Wang J, Li TJ, Ding JN, Cai LC, Su DD 2013: Oxidative stress-mediated signaling pathways: A review. J Food Agric Environ 11: 132-139
28. Zhu LH, Zhao KL, Chen XL, Xu JX 2012: Impact of weaning and an antioxidant blend on intestinal barrier function and antioxidant status in pigs. J Animal Sci 90: 2581-2589 <https://doi.org/10.2527/jas.2011-4444>
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  • ISSN 0001-7213 (printed)
  • ISSN 1801-7576 (electronic)

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