Acta Vet. Brno 2020, 89: 383-389
https://doi.org/10.2754/avb202089040383
The effect of capsaicin and diethylnitrosamine on mouse nephrotoxicity, hepatotoxicity and hepatocarcinogenesis
References
1. 2012: A comprehensive review of the carcinogenic and anticarcinogenic potential of capsaicin. Toxicol Pathol 40: 847-873
< K, Boorman G, Mohammad B, McKenzie D, Babbar S https://doi.org/10.1177/0192623312444471>
2. 2000: Curcumin-containing diet inhibits diethylnitrosamine-induced murine hepatocarcinogenesis. Carcinogenesis 21: 331-335
< SE, Kuo ML, Hsu CH, Chen CR, Lin JK, Lai GM, Hsieh CY, Cheng AL https://doi.org/10.1093/carcin/21.2.331>
3. 2014: The N-nitrosodiethylamine mouse model: sketching a timeline of evolution of chemically-induced hepatic lesions. Anticancer Res 34: 7029-7037
RM, Santos NP, Rocha AF, Colaço A, Lopes C, Oliveira PA
4. 1995: Genotoxic effects produced by capsaicin in mouse during subchronic treatment. Mutat Res 345: 3-4
< S, Madrigal-Bujaidar E, Calderón Montellano E, Ramírez Herrera L, Díaz García BD https://doi.org/10.1016/0165-1218(95)90046-2>
5. 2014: The potential antitumor effects of capsaicin. Prog Drug Res 68: 181-208
I, Rodríguez-Henche N
6. 1993: Proliferating cell nuclear antigen: a marker for hepatocellular proliferation in rodents. Environ Health Perspect 101: 211-218
< SR, Butterworth BE, Goldsworthy TL https://doi.org/10.1289/ehp.93101s5211>
7. 1937: Clinical manifestation and studies in parenchymatous hepatitis. Ann Intern Med 10: 1144-1155
HA
8. 2017: Review of hepatocellular carcinoma: Epidemiology, etiology, and carcinogenesis. J Carcinog 16: 1
YA, Mian I, Rowe JH
9. 2009: Experimental mouse models for hepatocellular carcinoma research. Int J Exp Pathol 90: 367-386
< F, Colle I, Van Vlierberghe H https://doi.org/10.1111/j.1365-2613.2009.00656.x>
10. 2018: Expression of glutamate transporters in mouse liver, kidney, and intestine. J Histochem Cytochem 66: 189-202
< QX, Ottestad-Hansen S, Holmseth S, Hassel B, Danbolt NC, Zhou Y https://doi.org/10.1369/0022155417749828>
11. 1988: The promoting effect of capsaicin on the development of diethylnicrosamine-initiated enzyme altered hepatic foci in male Sprague Dawley rats. J Korean Cancer Assoc 20: 1-8
JJ, Kim SH
12. 1991: Different modifying responses of capsaicin in a wide-spectrum initiation model of F344 rat. J Korean Med Sci 6: 31-36
< JJ, Cho KJ, Lee YS, Bae JH https://doi.org/10.3346/jkms.1991.6.1.31>
13. 2017: Enhanced susceptibility of Ogg1 mutant mice to multiorgan carcinogenesis. Int J Mol Sci 18: 1801
< A, Ishii N, Okuno T, Fujioka M, Gi M, Wanibuchi H https://doi.org/10.3390/ijms18081801>
14. 2013: Expression of epithelial cell adhesion molecule and proliferating cell nuclear antigen in diethylnitrosamine-induced hepatocarcinogenesis in mice. Exp Ther Med 5: 138-142
< JS, Kang HG, Park YI, Lee H, Park K, Lee YS, Kim S, Ryu DY https://doi.org/10.3892/etm.2012.751>
15. 2015: Current concepts in the immunohistochemical evaluation of liver tumors. World J Hepatol 7: 1403-1411
< AK, Salomao MA, Lagana SM https://doi.org/10.4254/wjh.v7.i10.1403>
16. 2011: Dose-related induction of hepatic preneoplastic lesions by diethylnitrosamine in C57BL/6 mice. Toxicol Pathol 39: 776-786
< M, Kamendulis LM, Peat TJ, Klaunig JE https://doi.org/10.1177/0192623311409596>
17. 2017: European cancer mortality predictions for the year 2017, with focus on lung cancer. Ann Oncol 28: 1117-1123
< M, Carioli G, Bertuccio P, Boffetta P, Levi F, La Vecchia C, Negri E https://doi.org/10.1093/annonc/mdx033>
18. 2014: Chemopreventive and therapeutic effect of capsaicin against diethylnitrosamine induced liver injury and hepatocellular carcinoma in rats. Int J Biol Pharm Res 5: 630-642
FZ, Sultan AS, Abas AM
19. 2006: Proliferating cell nuclear antigen (PCNA) activity in hepatocellular carcinoma, benign peri-neoplastic and normal liver. Malays J Pathol 28: 73-77
KS, Cheah PL, Baharudin NB, Looi LM
20. 1993: Proliferating cell nuclear antigen expression in normal, regenerative, and neoplastic liver: a fine-needle aspiration cytology and biopsy study. Hum Pathol 24: 905-908
< I, Ariza A, Llatjós M, Castellà E, Mate JL, Navas-Palacios JJ https://doi.org/10.1016/0046-8177(93)90141-3>
21. 2016: Structural and functional insight into proliferating cell nuclear antigen. J Microbiol Biotechnol 26: 637-647
< SY, Jeong MS, Han CW, Yu HS, Jang SB https://doi.org/10.4014/jmb.1509.09051>
22. 2015: Effects of caffeine on renal toxicity induced by diethylnitrosamine. Zahedan J Res Med Sci 17: 7-9
M, Rezaie A, Haghi-Karamallah M, Fazlara A, Shahriari A, Najafzadeh H
23. 2013: Effects of Echinacea purpurea on hepatic and renal toxicity induced by diethylnitrosamine in rats. Jundishapur J Nat Pharm Prod 8: 60-64
< A, Fazlara A, Haghi Karamolah M, Shahriari A, Najaf Zadeh H, Pashmforosh M https://doi.org/10.5812/jjnpp.9686>
24. 2012: Histology, bioenergetics and oxidative stress in mouse liver exposed to N-diethylnitrosamine. In Vivo 26: 921-929
NP, Pereira IC, Pires MJ, Lopes C, Andrade R, Oliveira MM, Colaço A, Peixoto F, Oliveira PA
25. 2014: N-diethylnitrosamine mouse hepatotoxicity: time-related effects on histology and oxidative stress. Exp Toxicol Pathol 66: 429-436
< NP, Colaço A, Gil da Costa RM, Oliveira MM, Peixoto F, Oliveira PA https://doi.org/10.1016/j.etp.2014.07.002>
26. 2012: Adaptive immunity suppresses formation and progression of diethylnitrosamine-induced liver cancer. Gut 61: 1733-1743
< C, Teufel A, Yevsa T, Staib F, Hohmeyer A, Walenda G, Zimmermann HW, Vucur M, Huss S, Gassler N, Wasmuth HE, Lira SA, Zender L, Luedde T, Trautwein C, Tacke F https://doi.org/10.1136/gutjnl-2011-301116>
27. 2006: Risk factors and mechanisms of hepatocarcinogenesis with special emphasis on alcohol and oxidative stress. Biol Chem 387: 349-360
< HK, Stickel F https://doi.org/10.1515/BC.2006.047>
28. 2013: Mechanisms and clinical uses of capsaicin. Eur J Pharmacol 720: 55-62
< SK, Vij AS, Sharma M https://doi.org/10.1016/j.ejphar.2013.10.053>
29. 2017: Cancer statistics, 2017. CA Cancer J Clin 67: 7-30
< RL, Miller KD, Jemal A https://doi.org/10.3322/caac.21387>
30. 1988: Distribution of glutamine synthetase and carbamoyl-phosphate synthetase I in vertebrate liver. Proc Natl Acad Sci USA 85: 160-164
< DD Jr, Campbell JW https://doi.org/10.1073/pnas.85.1.160>
31. Stewart BW, Wild CP 2014: World cancer report 2014. Lyon, France: International Agency for Research on Cancer
32. Stuver S, Trichopoulos D 2008: Cancer of the liver and biliary tract. In: Adami HO, Hunter DJ, Trichopoulos D (Eds.): Textbook of Cancer Epidemiology. Oxford University Press, New York, pp. 308-332
33. 2012: A novel antihepatitis drug, bicyclol, prevents liver carcinogenesis in diethylnitrosamine-initiated and phenobarbital-promoted mice tumor model. J Biomed Biotechnol 2012: 584728
H, Yu L, Wei H, Liu G
34. 2015: Diethylnitrosamine (DEN)-induced carcinogenic liver injury in mice. Lab Anim 49: 59-69
< R, Kraus T, Liedtke C, Schwarz M, Weiskirchen R https://doi.org/10.1177/0023677215570086>
35. 2011: Modulatory effects of capsaicin on N-diethylnitrosamine (DEN)-induced mutagenesis in Salmonella typhimurium YG7108 and DEN-induced hepatocarcinogenesis in gpt delta transgenic rats. Genes and Environment 33: 160-166
< N, Yasui Y, Takamune M, Yamada M, Muramatsu M, Masumura K, Ohta T, Tanaka T, Nohmi T https://doi.org/10.3123/jemsge.33.160>
36. 2018: Cytotoxic effect of aeruginosin-865, resveratrol and capsaicin on mouse fibroblasts and cells derived from fallow deer. Nat Prod Commun 13: 205-208
I, Celá Kolísková P, Kuchařová V, Tomenendálová J, Kováčová V, Pikula J, Repková B, Rapekta P, Hrouzek P, Cheel J, Doubek J
37. 2018: Contradictory effects of mitochondria- and non-mitochondria-targeted antioxidants on hepatocarcinogenesis by altering DNA repair in mice. Hepatology 67: 623-635
< B, Fu J, Yu T, Xu A, Qin W, Yang Z, Chen Y, Wang H https://doi.org/10.1002/hep.29518>
38. 2015: Roles of combined glypican-3 and glutamine synthetase in differential diagnosis of hepatocellular lesions. Asian Pac J Cancer Prev 16: 4769-4775
< RE, Shams Eldeen AA https://doi.org/10.7314/APJCP.2015.16.11.4769>
39. WHO 2018: Cancer. Available at: www.who.int/mediacentre/factsheets/fs297/en/. Last modified September 12, 2018
40. 2012: Fibrosis-dependent mechanisms of hepatocarcinogenesis. Hepatology 56: 769-775
< DY, Friedman SL https://doi.org/10.1002/hep.25670>