Acta Vet. Brno 2021, 90: 125-134
Monitoring the redox status in dairy cows by using plasma dROMs, PAT, and OSI biomarkers
The aim of this work was to determine the changes of redox indicators such as reactive oxygen metabolites (dROMs), plasma antioxidant test (PAT) and the oxidative stress index (OSI) in dairy cows at different stages of lactation using a diagnostic equipment which is suitable for in vivo oxidative stress (OS) monitoring procedures. In total, 628 dairy cows were examined in the pre-parturient period (days in milk [DIM]: -21 to -1 day; n = 117), in the calving and maternity period (DIM: 0 to 7; n = 137), in the early lactation period (DIM: 8 to 30; n = 139), and the in the peak lactation (DIM: 31 to 150; n = 235). The dROMs and OSI values were significantly different (P < 0.05) when comparing the 1st and 2nd+ lactation cows in each group. The highest mean value of dROMs was detected at the calving and maternity stage in 1st lactation cows (141 ± 25 U. Carr) and the lowest (103 ± 29 U. Carr) was found in peak lactation. The OSI developed similarly, with the highest value of 5.58 ± 0.94 in the calving and maternity period in the 1st lactation cows and the lowest value of 4.05 ± 1.21 in peak lactation and significant differences were found in many cases. Based on the results, the measurement of dROMs and OSI may be suitable for detecting oxidative stress in different lactation stages.
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Funding
The project was supported by the European Union and co-financed by the European Social Fund (grant agreement number: EFOP-3.6.2-16-2017-00012, project title: Development of a Product Chain Model for Functional, Healthy and Safe Foods from Farm to Fork Based on a Thematic Research Network; and grant agreement number: EFOP-3.6.1-16-2016-00024, project title: Institutional Developments for Intelligent Specialization in co-operation of the University of Veterinary Medicine and the Faculty of Agricultural and Food Sciences, Széchenyi István University).
