Neopterin, procalcitonin, total sialic acid, paraoxonase-1 and selected haematological indices in calves with aspiration pneumonia

Akyüz, Enes; Merhan, Oğuz; Aydın, Uğur; Sezer, Mert; Kuru, Mushap; Karakurt, Emin; Yıldız, Uğur; Bozukluhan, Kadir; Batı, Yusuf Umut; Yıldız, Ayfer; Gökce, Gürbüz

doi:10.2754/avb202291020115

Acta Veterinaria > Archive > 2022, Vol. 91 > Issue 2 > Neopterin, procalcitonin, total sialic…

Acta Vet. Brno 2022, 91: 115-124

https://doi.org/10.2754/avb202291020115

Neopterin, procalcitonin, total sialic acid, paraoxonase-1 and selected haematological indices in calves with aspiration pneumonia

Enes Akyüz¹

, Oğuz Merhan²

, Uğur Aydın³

, Mert Sezer¹

, Mushap Kuru⁴

, Emin Karakurt⁵

, Uğur Yıldız³

, Kadir Bozukluhan⁶

, Yusuf Umut Batı¹

, Ayfer Yıldız⁵

, Gürbüz Gökce¹

¹Kafkas University, Faculty of Veterinary Medicine, Department of Internal Medicine, Kars, Turkey
²Kafkas University, Faculty of Veterinary Medicine, Department of Biochemistry, Kars, Turkey
³Kafkas University, Faculty of Veterinary Medicine, Department of Surgery, Kars, Turkey
⁴Kafkas University, Faculty of Veterinary Medicine, Department of Obstetrics and Gynecology, Kars, Turkey
⁵Kafkas University, Faculty of Veterinary Medicine, Department of Pathology, Kars, Turkey
⁶Kafkas University, Kars Vocational School, Department of Veterinarian and Laboratory, Kars, Turkey

Received April 22, 2021
Accepted February 1, 2022

This study aims to determine serum neopterin, procalcitonin, total sialic acid (TSA), paraoxonase-1 (PON1), and some haematological indices in calves with aspiration pneumonia (ASP). The patient group consisted of 30 calves of the Simmental breed, 0–28 days old, diagnosed with ASP upon clinical examination, anamnesis, auscultation examination, and radiographic results. The control group consisted of 10 healthy calves, otherwise with the same characteristics. A significant difference was found between calves with ASP and the control group of calves in serum iron (Fe, P < 0.001), total iron-binding capacity (TIBC, P < 0.05), PON1, TSA, procalcitonin, neopterin, and total leukocyte count (WBC) indices as a result of the analyses (P < 0.001). Serum procalcitonin concentration was found to be 285.71 ng/ml in the ASP group and 30.34 ng/ml in the control group. Serum neopterin concentration was found to be 37.68 nmol/l in the ASP group and 15.14 nmol/l in the control group. Serum procalcitonin, neopterin, and TSA concentrations were found to be significantly higher in the ASP group compared to the control group. It was concluded that biomarkers such as serum procalcitonin, neopterin, and TSA are high in calves with ASP, and as a result, these markers provide diagnostically and prognostically important information.