Acta Vet. Brno 2022, 91: 309-315

https://doi.org/10.2754/avb202291040309

Phytotherapy compared to omeprazol therapy in equine gastric ulcers

Margaréta Kulcsár1, Michaela Karamanová1, František Novotný1, Zuzana Vilhanová1, Martina Pettenello1, Csilla Tóthová2

1University of Veterinary Medicine and Pharmacy, University Veterinary Hospital, Equine Clinic, Košice, Slovak Republic
2University of Veterinary Medicine and Pharmacy, University Veterinary Hospital, Clinic of Ruminants, Košice, Slovak Republic

Received December 14, 2021
Accepted October 10, 2022

References

1. Al-Snafi AE 2013: The pharmaceutical importance of Althaea officinalis and Althaea rosea: A review. Int J Pharm Technol Res 5: 1378-1385
2. Andrews F, Bernard W, Byars D 1999: Recommendations for the diagnosis and treatment of equine gastric ulcer syndrome (EGUS). Equine Vet Educ 11: 262-272
3. Bennett A, Clark-Wibberley T, Stamford IF, Wright JE 1980: Aspirin-induced gastric mucosal damage in rats: cimetidine and deglycyrrhizinated liquorice together give greater protection than low doses of either drug alone. J Pharm Pharmacol 32: 151 <https://doi.org/10.1111/j.2042-7158.1980.tb12879.x>
4. Butnariu M, Coradini CZ 2012: Evaluation of biologically active compounds from Calendula officinalis flowers using spectrophotometry. Chem Cent J 6: 35 <https://doi.org/10.1186/1752-153X-6-35>
5. Da Nagao Y, Sata M, Suzuki H, Tanikawa K, Itoh K, Kameyama T 1996: Effectiveness of glycyrrhizin for oral lichen planus in patients with chronic HCV infection. J Gastroenterol 31: 691-695 <https://doi.org/10.1007/BF02347618>
6. Farzaei MH, Rahimi R, Abbasabadi Z, Abdollahi M 2013: An evidence-based review on medicinal plants used for the treatment of peptic ulcer in traditional Iranian medicine. Int J Pharmacol 9: 108-124 <https://doi.org/10.3923/ijp.2013.108.124>
7. Henneke DR, Potter GD, Kreider JL, Yeates BF 1983: Relationship between condition score, physical measurements and body fat percentage in mares. Equine Vet J 15: 371-372 <https://doi.org/10.1111/j.2042-3306.1983.tb01826.x>
8. Ibrahim AM, Abdulqader A, Jaber M, Mohammed AS, Shoeb Q, Syed R 2006: Antisecretagogue, antiulcer and cytoprotective effects of ‘peppermint’ Mentha piperita L. in laboratory animals. J Med Sci 6: 930-936
9. Karbalay-Doust S, Noorafshan A 2009: Antiulcerogenic effects of Matricaria chamomilla extract in experimental gastric ulcer in mice. Iran J Med Sci 34: 198-203
10. MacAllister CG, Andrews FM, Deegan E, Ruoff W, Olovson SG 1997: A scoring system for gastric ulcers in the horse. Equine Vet J 29: 430-433 <https://doi.org/10.1111/j.2042-3306.1997.tb03154.x>
11. Masoomeh MJ, Kiarash G 2007: In vitro susceptibility of Helicobacter pylori to licorice extract. Iran J Pharm Res 6: 69-72
12. Morshedi M, Gol A, Mohammadzadeh A 2016: The effect of Matricaria chamomilla on the treatment of ibuprofen-induced gastric ulcers in male rats. Hormozgan Med J 20: 270-275
13. Murray MJ, Grodinsky C, Anderson CW, Radue PF, Schmidt RG 1989: Gastric ulcers in horses: a comparison of endoscopic findings in horses with and without clinical signs. Equine Vet J Suppl 7: 68-72 <https://doi.org/10.1111/j.2042-3306.1989.tb05659.x>
14. Nazim AM, Difuza E 2019: Phytochemical constituents and pharmacological effects of licorice. In: Ozturk M, Hakeem KR (Eds): Plant and Human Health, Volume 3. Springer Cham, Switzerland, pp 1-21
15. Niedźwiedź A, Kubiak K, Nicpoń J 2013: Endoscopic findings of the stomach in pleasure horses in Poland. Acta Vet Scand 55: 45 <https://doi.org/10.1186/1751-0147-55-45>
16. Rezq AA, Elmallh M 2010: Anti-ulcer effect of cinnamon and chamomile aqueous extracts in rat models. J Am Sci 6: 209-216
17. Sameh SZ, Basim AS, Ali AAS, Hekma AAEL 2015: Protective effects of ginger and marshmallow extracts on indomethacin-induced peptic ulcer in rats. J Nat Sci Biol Med 6: 421-428
18. Sargul HS, Sheila MN, Zahra AA, Hazem AAB, Nadir MQ 2020: Gastroprotective activity of Hypericum perforatum extract in ethanol-induced gastric mucosal injury in Wistar rats: A possible involvement of H+/K+ATPase α inhibition. Heliyon 6: e05249
19. Sykes BW, Hewetson M, Hepburn RJ, Luthersson N, Tamzali Y 2015a: European college of equine internal medicine 309 consensus statement-equine gastric ulcer syndrome in adult horses. J Vet Intern Med 29: 1288-1299 <https://doi.org/10.1111/jvim.13578>
20. Sykes BW, Sykes KM, Hallowell GD 2015b: A comparison of three doses of omeprazole in the treatment of equine gastric ulcer syndrome: a blinded, randomized, dose-response clinical trial. Equine Vet J 47: 285-290 <https://doi.org/10.1111/evj.12287>
21. Sykes BW, Jokisalo JM 2014: Rethinking equine gastric ulcer syndrome: Part 1 - terminology, clinical signs and diagnosis. Equine Vet Educ 26: 543-547 <https://doi.org/10.1111/eve.12236>
22. Szelenyi I, Isaac O, Thiemer K 1979: Pharmacological experiments with compounds of chamomile. III. Experimental studies of the ulcerprotective effect of chamomile. Planta Med 35: 218-227 <https://doi.org/10.1055/s-0028-1097208>
23. Van Marle J, Aarsen PN, Lind A, van Weeren-Kramer J 1981: Deglycyrrhizinised liquorice (DGL) and the renewal of rat stomach epithelium. Eur J Pharmacol 72: 219-225 <https://doi.org/10.1016/0014-2999(81)90276-4>
24. Woodward MC, Huff NK, Garza F, Keowen ML, Kearney MT, Andrews FM 2014: Effect of pectin, lecithin, and antacid 374 feed supplements (Egusin®) on gastric ulcer scores, gastric fluid pH and blood gas values in horses. BMC Vet Res 10: S4 <https://doi.org/10.1186/1746-6148-10-S1-S4>
front cover
  • ISSN 0001-7213 (printed)
  • ISSN 1801-7576 (electronic)

Current issue

Archive