Acta Vet. Brno 2023, 92: 303-307

https://doi.org/10.2754/avb202392030303

The effect of urine sample temperature on the efficacy of olfactory detection of prostate cancer in men by a specially trained dog

Lucie Urbanová1, Vlasta Vyhnánková2, Andrea Nečasová1, Zita Filipejová1, Robert Srnec1, Laura Staňková1, Ilaria Rizzo3, Dalibor Pacík2, Alois Nečas1

1University of Veterinary Sciences Brno, Faculty of Veterinary Medicine, Small Animal Clinic, Department of Surgery and Orthopaedics, Brno, Czech Republic
2University Hospital Brno, Department of Urology, Brno, Czech Republic
3Centro Cinofilo Abbaiare Stanca – Baulé a Stracha Pinerolo, Pinerolo, Italy

Received October 31, 2022
Accepted July 11, 2023

References

1. Bikov A, Lazar Z and Horvath I 2015: Established methodological issues in electronic nose research: how far are we from using these instruments in clinical settings of breath analysis? J Breath Res 9: 034001 <https://doi.org/10.1088/1752-7155/9/3/034001>
2. Buszewski B, Rudnicka J, Ligor T, Walczak M, Jezierski T, Amann A 2012: Analytical and unconventional methods of cancer detection using odor. Trends Anal Chem 38: 1e12 <https://doi.org/10.1016/j.trac.2012.03.019>
3. Cablk ME, Szelagowski EE, Sagebiel JC 2012: Characterization of the volatile organic compounds present in the headspace of decomposing animal remains, and compared with human remains. Forensic Sci Int 220: 118-125 <https://doi.org/10.1016/j.forsciint.2012.02.007>
4. Cornu JN, Cancel-Tassin G, Ondet V, Girardet C, Cussenot O 2010: Olfactory detection of prostate cancer by dogs sniffing urine: A step forvard in early diagnosis. Eur Urol 59: 197-201 <https://doi.org/10.1016/j.eururo.2010.10.006>
5. Craven BA, Paterson EG, Settles GS 2010: The fluid dynamics of canine olfaction: unique nasal airflow patterns as an explanation of macrosmia. J R Soc Interface 47: 933-943 <https://doi.org/10.1098/rsif.2009.0490>
6. DeGreeff LE, Weakley-Jones B, Furton KG 2012: Creation of training aids for human remains detection canines utilizing a non-contact, dynamic airflow volatile concentration technique. Forensic Sci Int 217: 32-38 <https://doi.org/10.1016/j.forsciint.2011.09.023>
7. Flanders FB 2011: Exploring Animal Science. Delmar Pub, NY, USA, 737 p.
8. Forbes SL, Rust LT, Trebilcock K, Perrault KA, McGrath LT 2014: Effect of age and storage conditions on the volatile organic compound profile of blood. Forensic Sci Med Pathol 10: 570-582 <https://doi.org/10.1007/s12024-014-9610-3>
9. Hackner K, Pleil J 2017: Canine olfaction as an alternative to analytical instruments for disease diagnosis: understanding dog personality to achieve reproducible results. J Breath Res 11: 012001 <https://doi.org/10.1088/1752-7163/aa5524>
10. Hoffman EM, Curran AM, Dulgerian N, Stockham RA, Eckenrode BA 2009: Characterisation of the volatile organic compounds present in the headspace of decomposing human remains. Forensic Sci Int 186: 6-13 <https://doi.org/10.1016/j.forsciint.2008.12.022>
11. Kateb B, Ryan MA, Homer ML, Lara LM, Yin Y, Higa K, Chen M Y 2009: Sniffing out cancer using the JPL electronic nose: a pilot study of a novel approach to detection and differentiation of brain cancer. Neuroimage 47 (Suppl 2): T5-T9 <https://doi.org/10.1016/j.neuroimage.2009.04.015>
12. Lorenzo N, Wan T, Harper RJ, Hsu Y, Chow M, Rose S, Furton KG 2003: Laboratory and field experiments used to identify Canis lupus var. familiaris active odor signature chemicals from drugs, explosives, and humans. Anal Bioanal Chem 376: 1212-1224 <https://doi.org/10.1007/s00216-003-2018-7>
13. Pirrone F, Albertini M 2017: Olfactory detection of cancer by trained sniffer dogs: A systematic review of the literature. J Vet Behav 19: 105-117 <https://doi.org/10.1016/j.jveb.2017.03.004>
14. Rebmann AJ, David E, Sorg MH, Koenig M 2000: Cadaver dog handbook: forensic training and tactics for the recovery of human remains. CRC Press, Boca Raton, 232 p.
15. Sonoda H, Kohnoe S, Yamazato T, Satoh Y, Morizono G, Shikata K, Morita M, Watanabe A, Morita M, Kakeji Y, Inoue F, Maehara Y 2011: Colorectal cancer screening with odour aterial by canine scent detection. Gut 60: 814-819 <https://doi.org/10.1136/gut.2010.218305>
16. Stadler S, Stefanuto PH, Byer JD, Brokl M, Forbes SL, Focant JF 2012: Analysis of synthetic canine training aids by comprehensive twodimensional gas chromatography–time of flight mass spectrometry. J Chromatogr A 1255: 202-206 <https://doi.org/10.1016/j.chroma.2012.04.001>
17. Statheropoulos M, Sianos E, Agapiou A, Georgiadou A, Pappa A, Tzamtzis N, Geiotaki H, Papageorgiou C, Kolostoumbis D 2005: Preliminary investigation of using volatile organic compounds from human expired air, blood and urine for locating entrapped people in earthquakes. J Chromatogr B 822: 112-117 <https://doi.org/10.1016/j.jchromb.2005.05.028>
18. Urbanová L, Vyhnánková V, Krisová Š, Pacík D, Nečas A 2015: Intensive training technique utilizing the dog’s olfactory abilities to diagnose prostate cancer in men. Acta Vet Brno 84: 77-82 <https://doi.org/10.2754/avb201585010077>
19. Vass AA, Smith RR, Thompson CV, Burnett MN, Dulgerian N, Eckenrode BA 2008: Odor analysis of decomposing buried human remains. J Forensic Sci 53: 384-391 <https://doi.org/10.1111/j.1556-4029.2008.00680.x>
20. Willis CM, Church SM, Guest CM, Cook WA, McCarthy N, Bransbury AJ, Church MRT, Church JCT 2004: Olfactory detection of human bladder cancer by dogs: a proof of principle study. BMJ 329: 712-714 <https://doi.org/10.1136/bmj.329.7468.712>
21. Yoel U, Gopas J, Ozer J, Peleg R, Shvartzman P 2015: Canine scent detection of volatile elements, characteristic of malignant cells, in cell cultures. Isr Med Assoc J 17: 567-570
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  • ISSN 0001-7213 (printed)
  • ISSN 1801-7576 (electronic)

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