Acta Vet. Brno 2023, 92: 369-373
https://doi.org/10.2754/avb202392040369
Lafora disease in a Chihuahua dog: a case report
References
1. 2020: Brain proton magnetic resonance spectroscopy findings in a Beagle dog with genetically confirmed Lafora disease. J Vet Intern Med 34: 1594-1598
< N, Beckmann K, Dennler M, Zölch N https://doi.org/10.1111/jvim.15799>
2. 2020: Cannabidiol-enriched extract reduced the cognitive impairment but not the epileptic seizures in a Lafora disease animal model. Cannabis Cannabinoid Res 5: 150-163
< E, Andrés-Benito P, Grau-Escolano J, Caltana L, Brusco A, Sanz P, Ferrer I https://doi.org/10.1089/can.2019.0005>
3. 2019: NHLRC1 dodecamer repeat expansion demonstrated by whole genome sequencing in a Chihuahua with Lafora disease. Anim Genet 50: 118-119
< LS, Maiolini A, Häni AK, Jagannathan V, Leeb T https://doi.org/10.1111/age.12756>
4. 1999: Age-related changes in the brain of the dog. Vet Pathol 36: 202-211
< D, Ferrer I, Pumarola M https://doi.org/10.1354/vp.36-3-202>
5. 2018: Accumulation of laforin and other related proteins in canine Lafora disease with EPM2B repeat expansion. Vet Pathol 55: 543-551
< JK, Thongtharb A, Shiga T, Azakami D, Saito M, Sato M, Morozumi M, Nakayama H, Uchida K https://doi.org/10.1177/0300985818758471>
6. 2018: Canine Lafora disease in the Chihuahua breed. Proceedings of the 31st Annual Symposium of the ESVN-ECVN, Copenhagen, Denmark. J Vet Intern Med 34: 488-530
I, Minassian B, Wang P, Ahonen S, Sanchez-Masian D
7. 1991: Early detection of skin and muscular involvement in Lafora disease. J Neurol 238: 217-220
< S, Zucconi M, Quattrini A, Nemni R, Comola M, Taccagni L, Smirne S https://doi.org/10.1007/BF00314784>
8. 2005: Novel glycogen synthase kinase 3 and ubiquitination pathways in progressive myoclonus epilepsy. Hum Mol Genet 14: 2727-2736
< H, Ianzano L, Zhao XC, Chan EM, Turnbull J, Scherer SW, Ackerley CA, Minassian BA https://doi.org/10.1093/hmg/ddi306>
9. 2012: Ontogeny of Lafora bodies and neurocytoskeleton changes in laforin-deficient mice. Exp Neurol 236: 131-140
< J, Avila-Costa MR, Guevara P, Guevara J, Duron RM, Bai D, Tanaka M,Yamakawa K, Delgado-Escueta AV https://doi.org/10.1016/j.expneurol.2012.04.008>
10. 2010: Characterisation of Lafora-like bodies and other polyglucosan bodies in two aged dogs with neurological disease. Vet J 183: 222-225
< M, Pérez L, Serafín A, Teijeira S, Navarro C, Pumarola M https://doi.org/10.1016/j.tvjl.2008.10.002>
11. 2021: Histochemical characteristics and distribution of lipofuscin and polyglucosan bodies in the brain of dogs more than 10 years old. Vet Glas 75: 57-68
< S, Vucicevic I, Marinkovic D, Kukolj V, Anicic M, Ristoski T, Nikolic S, Aleksic-Kovacevic S https://doi.org/10.2298/VETGL201002001N>
12. Rai A, Ganesh S 2019: Polyglucosan Bodies in Aged Brain and Neurodegeneration: Cause or Consequence? In: Rath P (Ed): Models, Molecules and Mechanisms in Biogerontology, pp. 57-89, Springer, Singapore
13. 2010: Sequestration of chaperones and proteasome into Lafora bodies and proteasomal dysfunction induced by Lafora disease-associated mutations of malin. Hum Mol Genet 19: 4726-4734
< SN, Maity R, Sharma J, Dey P, Shankar SK, Satishchandra P, Jana NR https://doi.org/10.1093/hmg/ddq407>
14. 2014: DNA screening for Lafora’s disease in miniature wire-haired dachshunds. Vet Rec 175: 568
< R https://doi.org/10.1136/vr.g7417>
15. 2002: Polyglucosan storage disease in a dog resembling Lafora’s disease. J Vet Intern Med 16: 201-207
T, Williams J, van Wilpe E
16. 2013: Neuronatin-mediated aberrant calcium signaling and endoplasmic reticulum stress underlie neuropathology in Lafora disease. J Biol Chem 288: 9482-9490
< J, Mukherjee D, Rao SN, Iyengar S, Shankar SK, Satishchandra P, Jana NR https://doi.org/10.1074/jbc.M112.416180>
17. 1978: Lafora like inclusion bodies in the digestive tract of the aged dog. Acta Neuropathol 44: 2017-222
Y, Akiyama K, Suu S
18. 2017: Lafora disease in miniature Wirehaired Dachshunds. PLoS ONE 12: e0182024
< L, Key G, Tauro A, Ahonen S, Wang P, Ackerley C, Minassian BA, Rusbridge C https://doi.org/10.1371/journal.pone.0182024>
19. 2021: Canine Lafora disease: an unstable repeat expansion disorder. Life (Basel) 11: 689
T, Ahonen S, Espadas-Santiuste I, Matiasek K, Sanchez-Masian D, Rupp S, Vandenberghe H, Rose J, Wang T, Wang P, Minassian BA, Rusbridge C
20. 2009: Lafora disease as a cause of visually exacerbated myoclonic attacks in a dog. Can Vet J 50: 963-967
AA, McMillan C, Cullen CL, Boston SE, Turnbull J, Minassian BA