Acta Vet. Brno 2024, 93: 135-140
https://doi.org/10.2754/avb202493020135
    Acute kidney injury in horses as a consequence of treatment with suxibuzone
References
1.  C, Garavaglia G, Cavalli M 2005: COX-1 and COX-2 inhibition in horse blood phenylbutazone, flunixin, carprofen and meloxicam: an in vitro analysis. Pharmacol Res 52: 302-306
            <https://doi.org/10.1016/j.phrs.2005.04.004>
        
        
    
        2.  LG, Tyler DE 1984: Phenylbutazone toxicosis in the horse: a clinical study. J Am Vet Med A 184: 699-703
            
        
        
    
        3.  VL, Blikslager AT 2015: The use of nonsteroidal anti‐inflammatory drugs in critically ill horses. J Vet Emerg Crit Care 25: 76-88
            <https://doi.org/10.1111/vec.12271>
        
        
    
        4.  FT, Vynckier L, Debackere M 1993: The disposition of suxibuzone in the horse. J Vet Pharmacol Ther 16: 283-290
            <https://doi.org/10.1111/j.1365-2885.1993.tb00175.x>
        
        
    
        5.  TJ 2022: Acute kidney injury and renal failure in horses. Vet Clin N Am-Equine 38: 13-24
            <https://doi.org/10.1016/j.cveq.2021.11.002>
        
        
    
        6.  MR, Hussein HS, El-Sebaei MG 2012: Evaluation of urinary variables as diagnostic indicators of acute kidney injury in Egyptian draft horses treated with phenylbutazone therapy. J Equine Vet Sci 32: 268-273
            <https://doi.org/10.1016/j.jevs.2011.09.072>
        
        
    
        7.  G, Olsen E, Siwinska N 2022: Biomarkers of kidney disease in horses: a review of the current literature. Animals 12: 2678
            <https://doi.org/10.3390/ani12192678>
        
        
    
        8.  DE, Soma LR 1983: Renal papillary necrosis in horses after phenylbutazone and water deprivation. Vet Pathol 20: 603-610
            <https://doi.org/10.1177/030098588302000512>
        
        
    
        9.  KW, McGuirk SM, MacWilliams PS, Cooley AJ 1989: Phenolsulfonphthalein pharmacokinetics and renal morphologic changes in adult pony mares with gentamicin-induced nephrotoxicosis. Am J Vet Res 50: 1848-1853
            
        
        
    
        10.  JA, Nabity MB 2016: Renal biomarkers in domestic species. Vet Clin Path 45: 28-56
            <https://doi.org/10.1111/vcp.12333>
        
        
    
        11.  HC, Winter JC, Merle R, Gehlen H 2022: Symmetric dimethylarginine and renal function analysis in horses with dehydration. Equine Vet J 54: 670-678
            <https://doi.org/10.1111/evj.13484>
        
        
    
        12.  CG, Morgan SJ, Borne AT, Pollet RA 1993: Comparison of adverse effects of phenylbutazone, flunixin meglumine, and ketoprofen in horses. J Am Vet Med A 202: 71-77
            <https://doi.org/10.2460/javma.1993.202.01.71>
        
        
    
        13.  L, Sabaté D, Segura D, Mayós I, Homedes J 2004: Lower gastric ulcerogenic effect of suxibuzone compared to phenylbutazone when administered orally to horses. Res Vet Sci 76: 145-149
            <https://doi.org/10.1016/j.rvsc.2003.10.004>
        
        
    
        14.  SL, Hughes KJ, Charman AL, Nielsen SG, Phillips, JK, Noble GK 2014: Effects of meloxicam and phenylbutazone on renal responses to furosemide, dobutamine, and exercise in horses. Am J Vet Res 75: 668-679
            <https://doi.org/10.2460/ajvr.75.7.668>
        
        
    
        15.  WK 1983: Renal medullary crest necrosis associated with phenylbutazone therapy in horses. Vet Pathol 20: 662-669
            <https://doi.org/10.1177/030098588302000602>
        
        
    
        16.  VL, Marr CM, Bailey M, Smith S 2019: Prevalence of acute kidney injury in a population of hospitalized horses. J Vet Intern Med 33: 2294-2301
            <https://doi.org/10.1111/jvim.15569>
        
        
    
        17.  HC, Esser MM 2020: The sick adult horse: renal clinical pathologic testing and urinalysis. Vet Clin N Am-Equine 36: 121-134
            <https://doi.org/10.1016/j.cveq.2019.12.003>
        
        
    
        18.  HC, Gallant LR, Coyne M, Murphy R, Cross J, Strong‐Townsend M, Szlosek D, Yerramilli M, Li J 2021: Symmetric dimethylarginine and creatinine concentrations in serum of healthy draft horses. J Vet Intern Med 35: 1147-1154
            <https://doi.org/10.1111/jvim.16042>
        
        
    
        19.  N, Zak A, Slowikowska M, Niedzwiedz A, Paslawska U 2020: Serum symmetric dimethylarginine concentration in healthy horses and horses with acute kidney injury. BMC Vet Res 16: 1-6
            <https://doi.org/10.1186/s12917-020-02621-y>
        
        
    
        20.  N, Zak A, Paslawska U 2021: Detecting acute kidney injury in horses by measuring the concentration of symmetric dimethylarginine in serum. Acta Vet Scand 63: 1-10
            <https://doi.org/10.1186/s13028-021-00568-0>
        
        
    
        21.  DH, Douglas TA, Thompson H, Parkins JJ, Holmes PH 1981: Phenylbutazone toxicosis in equidae: a biochemical and pathophysiological study. Am J Vet Res 42: 1754-1759
            
        
        
    
        22.  A 1999: Nephrotoxicity of nonsteroidal anti-inflammatory drugs: physiologic foundations and clinical implications. Am J Med 106: 13S-24S
            <https://doi.org/10.1016/S0002-9343(99)00113-8>
        
        
    
 
        
