Acta Vet. Brno 2026, 95: 53-61
https://doi.org/10.2754/avb202695010053
Breed club requirements for breeding approval of dogs in relation to the prevention of genetically determined diseases
References
1. M, Chaudieu G, Hamel C, Lagoutte L, Gaël Manes G, Botherel N, Brabet P, Pilorge P, André C, Quignon P 2019: Natural models for retinitis pigmentosa: progressive retinal atrophy in dog breeds. Hum Genet 138: 441-453
<https://doi.org/10.1007/s00439-019-01999-6>
2. N, Owen M 2008: Canine elbow dysplasia 1. Aetiopathogenesis and diagnosis. In Pract 30: 508-512
<https://doi.org/10.1136/inpract.30.9.508>
3. F, Paci G, Spaterna A, Ciampolini R 2016: Morphological traits and inbreeding depression in Bracco Italiano dog breed. Ital J Anim Sci 14: 3721
<https://doi.org/10.4081/ijas.2015.3721>
4. RE 1992: Common ocular problems of Shih-tzu dogs. Can Vet J 33: 390-393
5. LM, Asher L, Summers JF, Diesel G, McGreevy PD 2010: Welfare epidemiology as a tool to assess the welfare impact of inherited defects on the pedigree dog population. Anim Welf 19: 67-75
<https://doi.org/10.1017/S0962728600002256>
6. LM, Asher L, Summers J, McGreevy P 2011: Getting priorities straight: Risk assessment and decision-making in the improvement of inherited disorders in pedigree dogs. Vet J 189: 147-154
<https://doi.org/10.1016/j.tvjl.2011.06.012>
7. F, Broeckx B, Verelst E, Deforce D, Saunders J, Duchateau L, Verhoeven G 2014: Combined prevalence of inherited skeletal disorders in dog breeds in Belgium. Vet Comp Orthop Traumatol 27: 395-397
8. LL, Schoenebeck JJ, Wiener P, Clements DN, Summers KM 2015: The challenges of pedigree dog health: Approaches to combating inherited disease. Canine Genet Epidemiol 2: 3
<https://doi.org/10.1186/s40575-015-0014-9>
9. A, Barrs V, Awad M, Child G, Brunel L, Mooney E, Martinez-Taboada F, McDonald B, McGreevy P 2019: Consequences and management of canine brachycephaly in veterinary practice: Perspectives from Australian veterinarians and veterinary specialists. Animals 9: 3
<https://doi.org/10.3390/ani9010003>
10. Z, Kosková B, Nečasová A, Urbanová L, Linhart P, Procházka D, Fiedler M, Nečas A 2024: The prevalence of dilated cardiomyopathy in the Weimaraner dog breed. Acta Vet Brno 93: 27-35
<https://doi.org/10.2754/avb202493010027>
11. KN, Wallace MR, Andrew SE, MacKay EO, Samuelson DA 2003: Cataracts in the Bichon Frise. Vet Ophthalmol 6: 3-9
<https://doi.org/10.1046/j.1463-5224.2003.00258.x>
12. A, Di Girolamo N, Corvi R, Santillo D, Andreani V, Pinzo B 2018: Epidemiology of ocular disorders presumed to be inherited in three small Italian dog breeds in Italy. Vet Ophthalmol 21: 524-529
<https://doi.org/10.1111/vop.12542>
13. Å 2020: Swedish experiences from 60 years of screening and breeding programs for hip dysplasia—research, success, and challenges. Front Vet Sci 7: 228
<https://doi.org/10.3389/fvets.2020.00228>
14. MS, Joya-Cadena JD, Villegas DF 2020: A mechanism synthesis and modeling for correction of hip dysplasia in medium and large dog breeds. Rev UIS Ing 19: 279-286
<https://doi.org/10.18273/revuin.v19n4-2020023>
15. S, Butterworth SJ, Miller A, Keeley B, Baines S, Mckee WM 2014: Lateral patellar luxation in dogs: a retrospective study of 65 dogs. Vet Comp Orthop Traumatol 27: 130-134
16. F, András B, Akos MA, Zoltán D, György FS 2007: Canine hip dysplasia 1: Role of genetic and environmental factors. Magy Allatorvosok Lapja 129: 354-360
17. RI, Trangerud C, Nodtvedt A, Dohoo I, Moe L, Sævik BK 2012: The effect of radiological hip dysplasia and breed on survival in a prospective cohort study of four large dog breeds followed over a 10 year period. Vet J 193: 206-211
<https://doi.org/10.1016/j.tvjl.2011.10.015>
18. M, Paloheimo A, Saloniemi H 2000: Attitudes of Finnish dog-breeders about programs to control canine genetic diseases. Prev Vet Med 43: 159-175
<https://doi.org/10.1016/S0167-5877(99)00100-2>
19. RS, Makgahlela ML, Nephawe KA, Mtileni B 2022: Evaluation of genetic diversity in dog breeds using pedigree and molecular analysis: A review. Diversity 14: 1054
<https://doi.org/10.3390/d14121054>
20. M 2010: Congenital deafness in the dog. Veterinaria 24: 57-60
21. CD, Ortega-Del Vecchyo D, O’Brien DP, Taylor JF, Ramirez O, Vilà C, Marques-Bonet T, Schnabel RD, Wayne RK, Lohmueller KE 2016: Bottlenecks and selective sweeps during domestication have increased deleterious genetic variation in dogs. Proc Natl Acad Sci USA 113: 152-157
<https://doi.org/10.1073/pnas.1512501113>
22. L, Child G 2026: Syringomyelia in Australian Cavalier King Charles spaniels: prevalence and changes over 16 years of magnetic resonance imaging screening. Aust Vet J in press 104: 50-56
<https://doi.org/10.1111/avj.70013>
23. C 2013: DNA testing: diagnosing and preventing inherited disorders in dogs. Vet Rec 172: 264-265
<https://doi.org/10.1136/vr.f1381>
24. CS 2014: The genetics of eye disorders in the dog. Canine Genet Epidemiol 1: 3
<https://doi.org/10.1186/2052-6687-1-3>
25. NS 1999: Inherited arrhythmias in the dog: potential experimental models of cardiac disease. Cardiovasc Res 44: 37-46
<https://doi.org/10.1016/S0008-6363(99)00198-4>
26. FW, Crook A, Sargan DR 2011: Internet resources cataloguing inherited disorders in dogs. Vet J 189: 132-135
<https://doi.org/10.1016/j.tvjl.2011.06.009>
27. AM, Keller GG, Famula TR 2017: Long-term genetic selection reduced prevalence of hip and elbow dysplasia in 60 dog breeds. PLoS One 12: e0172918
<https://doi.org/10.1371/journal.pone.0172918>
28. J, Korim P, Chudy M, Kvokacka V, Korimová J, Nagyová A 2025: Enhancing animal welfare through education of representatives of citizens associations aimed at animal rescue and protection-a review. Acta Vet Brno 94: 119-128
<https://doi.org/10.2754/avb202594020119>
29. HG, Dreger DL, Rimbault M, Davis BW, Mullen AB, Carpintero-Ramirez G, Ostrander EA 2017: Genomic analyses reveal the influence of geographic origin, migration, and hybridization on modern dog breed development. Cell Rep 19: 697-708
<https://doi.org/10.1016/j.celrep.2017.03.079>
30. N, Liu H, Theilen G, Sacks B 2013: The effects of dog breed development on genetic diversity and the relative influences of performance and conformation breeding. J Anim Breed Genet 130: 236-248
<https://doi.org/10.1111/jbg.12017>
31. I 2006: Canine genomics: Inherited diseases in dogs. Kleintierpraxis 51: 527-530
32. M, Giza E, Wrzosek M 2016: Evaluation of the occurrence of canine congenital sensorineural deafness in puppies of predisposed dog breeds using the brainstem auditory evoked response. Acta Vet Hung 64: 425-435
<https://doi.org/10.1556/004.2016.040>
33. R, Saponaro V, Carlucci L, Perego M, Battaia S, Borgarelli M 2021: Heart rhythm characterization during sudden cardiac death in dogs. J Vet Cardiol 38: 18-30
<https://doi.org/10.1016/j.jvc.2021.09.005>
34. A, Dreger DL, Frattini S, Polli M, Marelli S, Harris AC, Liotta L, Cocco R, Hogan AN, Bigi D, Caniglia R, Parker HG, Pagnacco G, Ostrander EA, Crepaldi P 2018: Studies of modern Italian dog populations reveal multiple patterns for domestic breed evolution. Ecol Evol 8: 2911-2925
<https://doi.org/10.1002/ece3.3842>
35. P, Sánchez-Molano E, Clements DN, Woolliams JA, Haskell MJ, Blott SC 2017: Genomic data illuminates demography, genetic structure and selection of a popular dog breed. BMC Genomics 18: 609
<https://doi.org/10.1186/s12864-017-3933-x>
36. BM, Llewellyn-Zaidi AM, Evans KM, O’Neill DG, Lewis TW 2017: Large-scale survey to estimate the prevalence of disorders for 192 Kennel Club registered breeds. Canine Genet Epidemiol 4: 8
<https://doi.org/10.1186/s40575-017-0047-3>
37. B, Nicholas FW, Thomson PC 2011: Selection against canine hip dysplasia: Success or failure? Vet J 189: 160-168
<https://doi.org/10.1016/j.tvjl.2011.06.014>

