Acta Vet. Brno 2008, 77: 277-284

Biomaterials and Stem Cells in the Treatment of Articular Cartilage, Meniscal, Physeal, Bone, Ligamentous and Tendineous Defects

A. Nečas1, L. Plánka2, R. Srnec1, P. Raušer1, L. Urbanová1, J. Lorenzová1, M. Crha1, J. Jančář3, P. Gál2

1Department of Surgery and Orthopaedics, Small Animal Clinic, Faculty of Veterinary Medicine, University of Veterinary and Pharmaceutical Sciences Brno, Czech Republic
2Department of Pediatric Surgery, Orthopaedics and Traumatology, Faculty Hospital Brno, Czech Republic
3Institute of Materials Chemistry, Brno University of Technology, Czech Republic

Received November 14, 2007
Accepted February 14, 2008

This review briefly summarizes existing results and main trends in experimental studies dealing with the possibilities of the use of biomaterials and mesenchymal stem cells in the treatment of diseases affecting tissues derived from the mesoderm, i.e. articular cartilage, meniscus, physis, bone, ligaments and tendons. The aim of these experimental studies is to find optimal forms of treatment of the diseases of individual parts of the musculoskeletal system using methods of tissue engineering with the use of stem cell transplantation.