Acta Vet. Brno 2015, 84: 305-311

Early pain management after periodontal treatment in dogs – comparison of single and combined analgesic protocols

Petr Raušer1, Petr Janalík1, Martina Klimešová1, Magdaléna Marková1, Ladislav Stehlík2, Tomáš Fichtel1

1University of Veterinary and Pharmaceutical Sciences Brno, Faculty of Veterinary Medicine, Small Animal Clinic, Department of Surgery and Orthopaedics, Brno, Czech Republic
2University of Veterinary and Pharmaceutical Sciences Brno, Faculty of Veterinary Medicine, Small Animal Clinic, Department of Diagnostic Imaging, Brno, Czech Republic

Received July 18, 2014
Accepted May 13, 2015

The aim of this study was to assess the analgesic effectiveness of three analgesic protocols in dogs undergoing a periodontal treatment. The study was performed as a prospective, randomized, “double blind” clinical study. A total of 45 client-owned dogs scheduled for periodontal treatment were included. Dogs of Group C received carprofen (4 mg·kg-1), dogs of Group B received bupivacaine (1 mg·kg-1) and dogs of Group CB received a combination of carprofen (4 mg·kg-1) and bupivacaine (1 mg·kg-1). Carprofen was administered subcutaneously 30 min before anaesthesia, bupivacaine was administered by nerve blocks in anaesthetized dogs. Painful periodontal treatment was performed in all patients, lasting up to one hour. Modified University of Melbourne Pain Score (UMPS), Visual Analogue Scale for pain assessment (VAS), plasma glucose and serum cortisol levels were assessed 30 min before administration of analgesics (C-0, B-0, CB‑0) and 2 h after recovery from anaesthesia (C-2, B-2, CB-2). For statistical analysis Friedman test, Mann-Whitney U-test, ANOVA and Fischer exact tests were used (P < 0.05). In CB‑2 compared to CB‑0 significantly decreased modified UMPS values. In CB‑2 UMPS values were significantly lower compared to C‑2 or B‑2. In C‑2 VAS values were significantly increased compared to C‑0, and in B‑2 VAS values were significantly increased compared to B‑0. Visual Analogue Scale values were significantly lower in CB‑2 compared to C‑2 or B‑2. Significantly increased plasma glucose concentrations were found in C‑2 compared to C‑0 and in B‑2 compared to B‑0. No other significant differences were detected. Administration of carprofen, bupivacaine or their combination is sufficient for early postoperative analgesia following periodontal treatment. Carprofen-bupivacaine combination is superior to carprofen or bupivacaine administered separately.


This work was supported by the Ministry of Education, Youth and Sports (Research Project IGA VFU No. 60/2012/FVL).


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