Acta Vet. Brno 2019, 88: 57-63

Use of fascia lata autograft for repair of urinary bladder defect in rabbits

Muhammed Kaan Yonez1, Gultekin Atalan1, Mehmet Onder Karayigit2, Umut Alpman1

1University of Erciyes, Faculty of Veterinary Medicine, Department of Surgery, Kayseri, Turkey
2University of Cumhuriyet, Faculty of Veterinary Medicine, Department of Pathology, Sivas, Turkey

Received August 7, 2018
Accepted February 12, 2019

The aim of this study was to investigate the compatibility of a fascia lata autograft for urinary bladder tissue defect, to evaluate the biomechanical, radiographical, macroscopical, biochemical, and histopathological test findings, and early and late complications of the surgical processes in rabbits. Thirty two adult healthy New Zealand rabbits were randomly allocated to 4 different groups of 8 animals. A 2 × 2 cm urinary bladder defect was repaired by the same size of fascia lata in experimental groups (Group 1, 2, 3). Rabbits in Group 1, 2 and 3 were euthanized at the end of the 4th, 8th and 12th week after surgeries, respectively. No surgical procedure was carried out for the urinary bladder of the rabbits in the control group, but their urinary bladders were used for biomechanical tests and the values compared with those of Group 1, 2 and 3. Histopathological examination of the grafted area was performed. The grafted area was consistent with that of the tissue of urinary bladder. No significant difference was found between the urinary bladder and the grafted area. No differences in biomechanical tests were recorded between grafted and ungrafted urinary bladders. Histopathologically, fascia lata turned into a normal urinary bladder tissue. Therefore, a fascia lata autograft can be succesfully used in urinary bladder defects. Fascia lata grafts can be used successfully in pathological conditions of the urinary bladder that require a new tissue.


This study was supported by Erciyes University Scientific Research Projects Unit project number TDK-2016-6356.


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